phosphodiesterases


phosphodiesterases
   A class of nucleases, because the reaction that they catalyze is the cleavage of phosphodiester bonds by H2O.

Forensic science glossary. . 2012.

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  • phosphodiesterases — Enzymes (EC 3.1.4.x) cleaving phosphodiester bonds, such as those in cAMP or between nucleotides in nucleic acid s, liberating smaller poly or oligonucleotide units or mononucleotides but not orthophosphate. SYN: phosphodiester hydrolases. spleen …   Medical dictionary

  • cyclic nucleotide phosphodiesterases — Often casually referred to simply as phosphodiesterases. Multiple isoenzymes are known. PDE I is calcium/calmodulin regulated and important in CNS and vasorelaxation, PDE II is cGMP stimulated and hydrolyzes cAMP. PDE III regulates vascular and… …   Dictionary of molecular biology

  • PDE — Phosphodiesterases (Fosfodiesterasas) …   Diccionario de siglas médicas y otras abreviaturas

  • Phosphodiesterase — A phosphodiesterase is any enzyme that breaks a phosphodiester bond. Usually, people speaking of phosphodiesterase are referring to cyclic nucleotide phosphodiesterases, which have great clinical significance and are described below. However,… …   Wikipedia

  • PDE7A — Phosphodiesterase 7A PDB rendering based on 1zkl …   Wikipedia

  • Phosphodiesterase 2 — The PDE2 (phosphodiesterase 2) enzyme is one of 21 different phosphodiesterases (PDE) found in mammals. These different PDEs can be subdivided to 11 families (PDE1 – PDE11). The different PDEs of the same family are functionally related despite… …   Wikipedia

  • PDE1 — (phosphodiesterase1) is a phosphodiesterase enzyme also known as calcium and calmodulin dependent phosphodiesterase. It is one of the 11 families of phosphodiesterase (PDE1 PDE11). PDE1 has three subtypes, PDE1A, PDE1B and PDE1C which divide… …   Wikipedia

  • PDE2 — The PDE2 (phosphodiesterase 2) enzyme is one of 21 different phosphodiesterases (PDE) found in mammals. These different PDEs can be subdivided to 11 families (PDE1 – PDE11). The different PDEs of the same family are functionally related despite… …   Wikipedia

  • PDE4B — Phosphodiesterase 4B, cAMP specific PDB rendering based on 1f0j …   Wikipedia

  • PDE4D — Phosphodiesterase 4D, cAMP specific PDB rendering based on 1mkd …   Wikipedia


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